Description

3-Fluoro-N,n-Diethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a high-value, advanced pharmaceutical intermediate featuring a protected boronic ester group on an aniline scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling efficient cross-coupling reactions like the Suzuki-Miyaura reaction for constructing complex molecules. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring fluorinated aromatic structures.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Employed in creating fluorescent probes, bioconjugation reagents, and other tools for biological research and diagnostics.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and process development projects for global clients.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	3-Fluoro-N,n-Diethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	2121511-42-8
Molecular Formula	C₁₆H₂₅BFNO₂
Molecular Weight	293.19 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-fluoro-N,N-diethylaniline; 3-Fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-diethylbenzenamine; 3-Fluoro-N,N-diethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenamine; N,N-Diethyl-3-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; 2121511-42-8; Boronic acid, B-[3-(diethylamino)-5-fluorophenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 3-Fluoro-N,n-Diethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The container should be kept tightly sealed under an inert atmosphere to maximize shelf life and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.