Description

tert-Butyl 5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pentanoate is a high-purity, protected boronic ester derivative used as a critical synthetic intermediate. This compound matters for its role in enabling precise carbon-carbon bond formation, particularly in the synthesis of complex molecules where functional group compatibility is essential. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing advanced scaffolds and active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for introducing pentanoate-tethered boronate functionality into target molecules, enabling the synthesis of complex organic compounds.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for creating novel drug candidates with specific chain-length spacers.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and insecticides requiring tailored hydrophobic side chains.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials where the boronate ester group acts as a handle for further modification.
• Chemical Biology Probes: Useful for creating labeled molecules or probes due to the reactivity of the boronate ester moiety in bioconjugation and tagging strategies.
• Process Chemistry & Scale-up: Provides a stable, protected form of the boronic acid for reliable and scalable manufacturing processes in fine chemical production.

Basic Information

Product Name	tert-Butyl 5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pentanoate
CAS No.	2114335-58-7
Molecular Formula	C15H29BO4
Molecular Weight	284.20 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pentanoic acid tert-butyl ester; tert-Butyl 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pentanoate; 2-(5-tert-Butoxy-5-oxopentyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pentanoic acid, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester; Boric acid, B-[5-[(1,1-dimethylethoxy)carbonyl]pentyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged use or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.