Description

m-Peg8-(Ch2)12-Phosphonic Acid Ethyl Ester is a specialized, high-purity functionalized PEG-phosphonate derivative designed for advanced material science and bioconjugation applications. This compound matters for its unique bifunctional structure, combining a hydrophilic polyethylene glycol (PEG) spacer with a phosphonic acid ethyl ester moiety, offering superior surface modification and linker capabilities. It is essential for researchers and manufacturers in the pharmaceutical, nanotechnology, and specialty polymer industries who require precise molecular tools for creating stable, functionalized surfaces and targeted delivery systems.

Application

• Surface Functionalization Agent: Used to modify metal oxide surfaces (e.g., titanium, silica) for improved biocompatibility, corrosion resistance, or to create reactive platforms for further chemistry.
• Bioconjugation Linker: Serves as a heterobifunctional crosslinker for attaching biomolecules (proteins, peptides) to nanoparticles, diagnostic assays, or therapeutic carriers, leveraging the phosphonate group for stable anchoring.
• Nanoparticle Stabilizer & Capping Agent: Imparts steric stabilization and functional handles to quantum dots, iron oxide, and other inorganic nanoparticles in aqueous media.
• Polymer Additive & Modifier: Incorporated into polymer matrices to enhance surface properties, introduce hydrophilicity, or create reactive sites for grafting.
• Dental & Bone Cement Modifier: Potential application in improving the adhesion and integration of biomaterials to bone or dental implants.
• Lubricant & Anti-wear Additive: The phosphonate group can act as an effective boundary lubricant and corrosion inhibitor in advanced lubricant formulations.
• Chelating Agent Precursor: The phosphonic acid ester can be hydrolyzed to form a chelating agent for metal ions in separation or catalysis.
• Research Chemical: A key intermediate in organic synthesis and materials research for developing novel drug delivery systems and smart materials.

Basic Information

Product Name	m-Peg8-(Ch2)12-Phosphonic Acid Ethyl Ester
CAS No.	2112737-70-7
Molecular Formula	C31H65O13P
Molecular Weight	676.82 g/mol
Synonyms	8-Aza-3,6,9,12,15,18,21,24-octaoxapentacosan-1-ylphosphonic acid ethyl ester; Ethyl 12-(2-(2-(2-(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)dodecylphosphonate; mPEG8-C12-Phosphonate Ethyl Ester; Phosphonic acid, P-[12-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]dodecyl]-, ethyl ester; OEG-Phosphonate C12 Ester; Heterobifunctional PEG Phosphonate Ester; PEGylated C12 Phosphonic Acid Ester
EINECS	Contact for details

Quality Control

Our m-Peg8-(Ch2)12-Phosphonic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial applications. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 90.0% (by NMR)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.