Description

Benzenamine, 4-Fluoro-N,n-Bis[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]- is a high-value, advanced pharmaceutical intermediate featuring a unique molecular architecture with multiple boronic ester functionalities. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex biaryl systems. It is primarily sought after by research institutions and pharmaceutical R&D departments for the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing complex drug candidates, especially those containing fluorinated biaryl motifs.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a precursor for organic semiconductors, OLED (Organic Light-Emitting Diode) materials, and metal-organic frameworks (MOFs).
• Chemical Synthesis: An essential reagent in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds under mild conditions.
• Ligand Synthesis: Can be utilized to create novel bidentate or polydentate ligands for catalysis and metal complexation.
• Life Science Tools: Potential use in the synthesis of probes and tags for biochemical assays and diagnostic applications.

Basic Information

Product Name	Benzenamine, 4-Fluoro-N,n-Bis[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]-
CAS No.	2106805-50-7
Molecular Formula	C30H35BB2FNO4
Molecular Weight	537.04 g/mol
Synonyms	4-Fluoro-N,N-bis[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]aniline; N,N-Bis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-4-fluoroaniline; 4-Fluoro-N,N-bis(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)benzenamine; Bis(4-pinacolatoboronphenyl)-4-fluoroaniline; 4-Fluoro-N,N-bis[4-(pinacolatoboryl)phenyl]aniline; Aniline, 4-fluoro-N,N-bis[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]- (IUPAC); Multi-Boronate Aniline Derivative
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict in-process controls to ensure batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, NMR (¹H, ¹³C, ¹¹B, ¹⁹F), and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent moisture absorption and decomposition of the boronic ester groups.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.