Description

2-Ethoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is a high-purity, advanced pharmaceutical intermediate and versatile synthetic building block. This compound is valued for its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the boronate ester functionality for selective coupling.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts for asymmetric synthesis.
• Polymer and Material Science: Incorporated into the backbone of specialty polymers, liquid crystals, and other advanced materials to modify electronic and physical properties.
• Academic and R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry research within university and corporate laboratories.

Basic Information

Item	Detail
Product Name	2-Ethoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile
CAS No.	2098425-93-3
Molecular Formula	C15H20BNO3
Molecular Weight	273.14 g/mol
Synonyms	4-Cyano-3-ethoxyphenylboronic acid pinacol ester; 2-Ethoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzonitrile; 3-Ethoxy-4-cyanophenylboronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-ethoxybenzonitrile; Pinacol 2-ethoxy-4-cyanophenylboronate
EINECS	Contact for details

Quality Control

Every batch of 2-Ethoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzonitrile is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and high purity. Our standard grade meets specifications suitable for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and GC is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.