Description

1-Cyclohexene-1-Carboxylic Acid, 3-(1-Ethylpropoxy)-4,5-Dihydroxy-, Ethyl Ester, (3R,4S,5R)- is a high-purity, stereochemically defined synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key chiral building block in the development of complex molecules, offering precise control over molecular architecture. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the research and development of novel therapeutic agents, particularly in complex synthetic pathways.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct stereogenic centers with high enantiomeric purity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, fragrances, and advanced materials requiring specific stereochemistry.
• Process Chemistry Development: Used in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Reference Standard: Acts as a high-purity analytical standard for method development and quality control in regulatory submissions.

Basic Information

Item	Details
Product Name	1-Cyclohexene-1-Carboxylic Acid, 3-(1-Ethylpropoxy)-4,5-Dihydroxy-, Ethyl Ester, (3R,4S,5R)-
CAS No.	2097777-49-4
Molecular Formula	C14H24O5
Molecular Weight	272.34 g/mol
Synonyms	(3R,4S,5R)-Ethyl 3-(1-ethylpropoxy)-4,5-dihydroxy-1-cyclohexene-1-carboxylate; (3R,4S,5R)-Ethyl 4,5-dihydroxy-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate; 1-Cyclohexenecarboxylic acid, 4,5-dihydroxy-3-(1-ethylpropoxy)-, ethyl ester, (3R,4S,5R)-; (3R,4S,5R)-3-(1-Ethylpropoxy)-4,5-dihydroxy-1-cyclohexene-1-carboxylic acid ethyl ester; CAS 2097777-49-4; Chiral Cyclohexene Derivative; Ethyl (3R,4S,5R)-3-(pentan-3-yloxy)-4,5-dihydroxycyclohex-1-enecarboxylate
EINECS	Contact for details

Quality Control

Our 1-Cyclohexene-1-Carboxylic Acid, 3-(1-Ethylpropoxy)-4,5-Dihydroxy-, Ethyl Ester, (3R,4S,5R)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Products undergo rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry, to confirm identity, stereochemical purity, and chemical purity. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.