Description

4-(Benzyl)Iminomethyl Phenyl-Boronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial protected boronic acid building block, offering enhanced stability for handling and storage compared to its free acid form. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for Suzuki-Miyaura cross-coupling reactions, a fundamental method for constructing biaryl and heterobiaryl scaffolds central to modern drug discovery.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific biaryl structures.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems.
• Scale-up and Process Chemistry: Suitable for use in kilogram-scale laboratory and pilot plant syntheses due to its improved handling properties.

Basic Information

Product Name	4-(Benzyl)Iminomethyl Phenyl-Boronic Acid Pinacol Ester
CAS No.	2097555-05-8
Molecular Formula	C21H26BNO2
Molecular Weight	335.25 g/mol
Synonyms	[4-[(Benzylamino)methyl]phenyl]boronic acid pinacol ester; N-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylamine; 4-((Benzylamino)methyl)benzeneboronic acid pinacol ester; 2-[4-[(Benzylamino)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; N-Benzyl-1-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methanamine; Boronic acid, B-[4-[(phenylmethyl)amino]methyl]phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-(Benzyl)Iminomethyl Phenyl-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.