Description

1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-Pyrrole-2,5-Dione is a high-value, multi-functional chemical building block that integrates a maleimide moiety with a protected boronic ester. This compound matters for its role as a key intermediate in advanced organic synthesis, particularly in cross-coupling reactions and the construction of complex pharmaceutical scaffolds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted drug candidates, especially those utilizing Suzuki-Miyaura cross-coupling for biaryl formation.
• Bioconjugation & Probe Development: The maleimide group enables selective thiol-Michael addition reactions for labeling proteins, antibodies, and other biomolecules in diagnostic and research applications.
• Polymer & Material Science: Used in the development of advanced polymers, dendrimers, and smart materials where the boronic ester and maleimide functionalities allow for controlled polymerization and post-polymerization modification.
• Agrochemical Synthesis: Acts as a building block for creating novel herbicides, fungicides, and insecticides with complex, targeted structures.
• Organic Electronic Materials: A potential monomer or intermediate in the synthesis of conjugated polymers and small molecules for OLEDs, OFETs, and other electronic devices.
• Chemical Biology Tool: Employed in the design of activity-based probes and inhibitors to study enzyme function and biological pathways.

Basic Information

Product Name	1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-Pyrrole-2,5-Dione
CAS No.	2096998-42-2
Molecular Formula	C16H18BNO4
Molecular Weight	299.13 g/mol
Synonyms	3-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)phenylboronic acid pinacol ester; 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)-1H-pyrrole-2,5-dione; 3-Maleimidophenylboronic acid pinacol ester; 1-(3-Boronophenyl)maleimide pinacol ester; N-(3-Boronophenyl)maleimide pinacol ester; 1H-Pyrrole-2,5-dione, 1-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-
EINECS	Contact for details

Quality Control

Every batch of 1-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)-1H-Pyrrole-2,5-Dione is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (including HPLC purity, NMR confirmation) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.