Description

2-(4-Chloro-3-Isopropoxy-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity organoboron building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. It is primarily utilized by pharmaceutical R&D teams, agrochemical manufacturers, and advanced material scientists for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific chlorinated aromatic systems.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular architecture is crucial.
• Ligand and Catalyst Development: Serves as a precursor for creating novel bidentate ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and protein interactions.
• Polymer Modification: Enables the functionalization of polymer chains to introduce specific aromatic groups, altering material properties.

Basic Information

Product Name	2-(4-Chloro-3-Isopropoxy-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	2096998-40-0
Molecular Formula	C15H22BClO3
Molecular Weight	296.59 g/mol
Synonyms	4-Chloro-3-isopropoxyphenylboronic acid pinacol ester; (4-Chloro-3-isopropoxyphenyl)boronic acid pinacol ester; 2-(4-Chloro-3-isopropoxy-phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Chloro-3-(1-methylethoxy)benzeneboronic acid pinacol ester; PINACOL (4-CHLORO-3-ISOPROPOXYPHENYL)BORONATE; 2096998-40-0; B-(4-Chloro-3-isopropoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-3-Isopropoxy-Phenyl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Assay	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.