Description

6-Chloro-3-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heteroaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional molecules. The CAS number for this compound is 2096998-30-8.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents for target identification and binding studies.
• Academic & Process R&D: A versatile reagent for method development and exploring new synthetic routes in academic and industrial laboratories.
• Ligand Synthesis: Useful for constructing complex ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	6-Chloro-3-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	2096998-30-8
Molecular Formula	C13H19BClNO2
Molecular Weight	267.56 g/mol
Synonyms	2-(6-Chloro-3-methylpyridin-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Chloro-3-methyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(6-Chloro-3-methyl-2-pyridinyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Chloro-3-methylpyridine-2-boronic acid pinacol ester; (6-Chloro-3-methylpyridin-2-yl)boronic acid pinacol ester; 2096998-30-8; 2-Pyridineboronic acid, 6-chloro-3-methyl-, 1,3,2-dioxaborolane deriv.
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Methyl-2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment. We adhere to cGMP principles for advanced intermediates to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.