Description

4-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Benzonitrile is a high-value, synthetically versatile boronic ester derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a key building block in modern organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A pivotal boron-containing reagent for forming carbon-carbon bonds in the synthesis of complex biaryl structures, a common motif in active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly in oncology, CNS, and antiviral therapeutic areas.
• Agrochemical Synthesis: Serves as a key precursor in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Liquid Crystal & OLED Material Research: Employed as a building block for creating organic electronic materials and advanced display components.
• Polymer Chemistry: Can be incorporated into polymer backbones or as a functional handle for post-polymerization modification to create specialty polymers.
• Chemical Biology & Proteomics: Utilized in the synthesis of probes and tags for studying biological processes and protein interactions.

Basic Information

Product Name	4-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Benzonitrile
CAS No.	2096998-25-1
Molecular Formula	C19H20BNO3
Molecular Weight	321.18 g/mol
Synonyms	4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)benzonitrile; 3-(4-Cyanophenoxy)phenylboronic acid pinacol ester; 4-[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]benzonitrile; 2-[3-(4-Cyanophenoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(3-Pinacolatoborylphenoxy)benzonitrile
EINECS	Contact for details

Quality Control

Our 4-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenoxy]Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR (1H, 13C, 11B), and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research and cGMP development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.