Description

1-(2-Methoxy-4-Nitrophenyl)-3-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is a specialized organic compound featuring a urea core linked to both a nitrophenyl and a boronic ester functionalized phenyl group. This unique structure makes it a valuable high-purity building block and key intermediate in advanced synthetic chemistry. It is primarily required by research institutions and pharmaceutical developers engaged in the creation of novel bioactive molecules, particularly those exploring proteolysis-targeting chimeras (PROTACs) and boron-based medicinal chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, especially those incorporating boron for targeted therapies.
• PROTAC Linker Component: Serves as a sophisticated chemical linker in the design and development of Proteolysis-Targeting Chimeras (PROTACs) due to its bifunctional structure.
• Chemical Biology Probe Synthesis: Used to create molecular probes for studying enzyme function and protein-protein interactions in biological systems.
• Organic Synthesis Building Block: Employed in advanced organic reactions, including Suzuki-Miyaura cross-coupling, leveraging its boronic ester moiety.
• Material Science Research: Investigated as a monomer or additive in the development of novel polymeric materials with specific optical or electronic properties.
• Agrochemical Intermediate: Potential use in the research and development of next-generation crop protection agents with novel modes of action.

Basic Information

Product Name	1-(2-Methoxy-4-Nitrophenyl)-3-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea
CAS No.	2096998-09-1
Molecular Formula	C20H24BN3O6
Molecular Weight	413.24 g/mol
Synonyms	3-(2-Methoxy-4-nitrophenyl)-1-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; 1-(2-Methoxy-4-nitrophenyl)-3-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; Urea, N-(2-methoxy-4-nitrophenyl)-N'-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; CAS 2096998-09-1; Boronic ester urea derivative; Nitrophenyl-boronated urea intermediate
EINECS	Contact for details

Quality Control

Our 1-(2-Methoxy-4-Nitrophenyl)-3-[3-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Urea is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support custom synthesis and can tailor specifications, including chiral purity, to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.