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2-[4-(Benzyloxy)-1-Naphthyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 2096997-27-0


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CAS No.:2096997-27-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-[4-(Benzyloxy)-1-Naphthyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the precise and efficient construction of complex organic molecules, which is critical for developing new materials and pharmaceuticals. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel chemical entities.

Application

  • Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aromatic rings, crucial for synthesizing complex biaryl structures found in active pharmaceutical ingredients (APIs) and organic electronic materials.
  • Pharmaceutical Intermediate Synthesis: Serves as a versatile building block in the multi-step synthesis of drug candidates, especially those containing naphthalene and benzyl-protected phenol moieties.
  • Agrochemical Research & Development: Used to create novel herbicides, fungicides, and insecticides by introducing specific aromatic subunits into lead molecules.
  • Material Science & OLED Development: Facilitates the synthesis of organic semiconductors, light-emitting materials, and charge-transport layers for next-generation display and lighting technologies.
  • Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands and catalysts used in asymmetric synthesis and other catalytic processes.
  • Academic & Contract Research: A vital tool for methodological development and exploratory synthesis in university laboratories and contract research organizations (CROs).

Basic Information

Product Name 2-[4-(Benzyloxy)-1-Naphthyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No. 2096997-27-0
Molecular Formula C23H27BO3
Molecular Weight 362.27 g/mol
Synonyms 4-(Benzyloxy)-1-naphthaleneboronic acid pinacol ester; 1-(Benzyloxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)naphthalene; 4-(Benzyloxy)naphthalen-1-ylboronic acid pinacol ester; 2-[4-(Benzyloxy)naphthalen-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; BN-NAP-OBn; (4-(Benzyloxy)naphthalen-1-yl)boronic acid pinacol ester; 1-(Benzyloxy)-4-(pinacolboranyl)naphthalene
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Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch of 2-[4-(Benzyloxy)-1-Naphthyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is characterized using advanced analytical techniques including NMR (1H, 13C, 11B), HPLC, and GC to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) with detailed chromatographic data and spectral information are available upon request. We adhere to strict internal quality protocols suitable for R&D and process development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage or when opening containers to prevent hydrolysis and maintain reactivity. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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