Description

2,3,6-Trimethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is a high-purity, advanced pharmaceutical intermediate featuring a pyridine core with a pinacol boronate ester functional group. This compound is a critical building block in modern medicinal chemistry, enabling efficient cross-coupling reactions for the synthesis of complex molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl systems in drug discovery pipelines.
• Pharmaceutical Intermediate: Serves as a versatile precursor in the synthesis of potential therapeutic agents targeting various diseases.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: A building block for creating organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the synthesis of labeled compounds for studying biological pathways and mechanisms.
• Process Chemistry & Scale-up: Supports the transition from laboratory-scale synthesis to commercial manufacturing of fine chemicals.

Basic Information

Product Name	2,3,6-Trimethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
CAS No.	2096997-24-7
Molecular Formula	C15H24BNO5
Molecular Weight	309.17 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3,6-trimethoxypyridine; 2,3,6-Trimethoxypyridine-5-boronic acid pinacol ester; Pyridine, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3,6-trimethoxy-; 2,3,6-Trimethoxy-5-pyridineboronic acid pinacol ester; 5-Borono-2,3,6-trimethoxypyridine pinacol ester
EINECS	Contact for details

Quality Control

Our 2,3,6-Trimethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.