Description

2-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isoquinolin-1(2H)-One is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the efficient and precise construction of complex molecular architectures, which is critical for developing new active compounds. This advanced intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on creating novel drug candidates, agrochemicals, and functional materials. The compound is supplied with a guaranteed high purity to ensure optimal performance and reproducibility in sensitive applications.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs), especially in oncology and CNS drug discovery.
• Agrochemical Research: Used to construct complex heterocyclic scaffolds for developing new generation herbicides, fungicides, and insecticides.
• Material Science: Serves as a building block for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand Synthesis: Employed in the preparation of sophisticated ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to tag or modify biomolecules for imaging and diagnostic applications due to its reactive boronate ester group.
• Academic & Industrial R&D: A vital tool for method development and exploring new chemical spaces in synthetic organic chemistry laboratories.

Basic Information

Product Name	2-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isoquinolin-1(2H)-One
CAS No.	2096997-20-3
Molecular Formula	C₁₉H₂₄BNO₃
Molecular Weight	325.21 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylisoquinolin-1(2H)-one; 2-Methyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-dihydroisoquinolin-1-one; 2-Methyl-1-oxo-1,2-dihydroisoquinoline-7-boronic acid pinacol ester; 7-Borono-2-methylisoquinolin-1(2H)-one pinacol ester; CAS 2096997-20-3
EINECS	Contact for details

Quality Control

Our 2-Methyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isoquinolin-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the product should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening the container to prevent moisture absorption. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.