Description

[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Thiazol-2-Yl-Methanol is a sophisticated boronic ester derivative that serves as a critical synthetic intermediate in modern organic chemistry. This compound is valued for its unique molecular architecture, combining a protected boronic acid moiety with a thiazole-methanol functional group, enabling precise cross-coupling reactions and the construction of complex heterocyclic scaffolds. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the thiazole ring for bioactivity.
• Material Science: Precursor for creating functionalized polymers and organic electronic materials with specific optoelectronic properties.
• Chemical Biology: Employed in the synthesis of probes and ligands for studying enzyme inhibition and protein interactions.
• Academic & R&D: Essential reagent for methodological development in synthetic organic chemistry laboratories worldwide.
• Custom Synthesis: Serves as a starting point for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	[3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Thiazol-2-Yl-Methanol
CAS No.	2096997-09-8
Molecular Formula	C16H20BNO3S
Molecular Weight	317.21 g/mol
Synonyms	2-(3-((2-Hydroxymethyl)thiazol-4-yl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-(2-(Hydroxymethyl)thiazol-4-yl)phenyl)boronic acid pinacol ester; 4-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)thiazole-2-methanol; B-[3-(2-Hydroxymethyl-4-thiazolyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol [3-(2-hydroxymethylthiazol-4-yl)phenyl]boronate; Thiazole boronic ester intermediate 2096997-09-8
EINECS	Contact for details

Quality Control

Our [3-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Thiazol-2-Yl-Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and full spectroscopic data are provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.