Description

Benzyl n-Butyl-n-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Carbamate is a specialized organoboron compound featuring a carbamate-protected amine and a boronic ester functional group. This molecular architecture makes it a valuable intermediate in modern synthetic chemistry, particularly for constructing complex molecules via cross-coupling reactions. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex drug candidates, especially those requiring Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of novel pesticides and herbicides where the boronic ester moiety enables precise molecular assembly.
• Material Science: Serves as a precursor for organic electronic materials, such as those used in OLEDs or organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of activity-based probes and bioconjugation reagents targeting serine hydrolases.
• Polymer Chemistry: Acts as a functional monomer or chain-transfer agent in the synthesis of specialty polymers with tailored properties.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	Benzyl n-Butyl-n-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Carbamate
CAS No.	2096994-88-4
Molecular Formula	C25H34BNO4
Molecular Weight	423.35 g/mol
Synonyms	Benzyl Butyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate; N-Benzyloxycarbonyl-N-butyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; 4-(N-Benzyloxycarbonyl-N-butylamino)phenylboronic acid pinacol ester; BOC-Protected Aminophenylboronic Ester; (4-((Benzyloxycarbonyl)(butyl)amino)phenyl)boronic acid pinacol ester; Z-Butyl-4-Bpin-aniline; CAS 2096994-88-4
EINECS	Contact for details

Quality Control

Our high-purity organoboron intermediates are manufactured under strict quality systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and NMR (1H, 13C, 11B) for structural confirmation, to ensure compliance with rigorous R&D and cGMP starting material standards. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent hydrolysis of the boronic ester group.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.