Description

1-(2,4-Dimethylphenyl)-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Urea is a sophisticated organic compound featuring a urea core linked to a pinacol boronate ester, making it a valuable intermediate for advanced chemical synthesis. This compound is specifically engineered for applications requiring precise molecular coupling, such as in the development of pharmaceuticals and functional materials. It is primarily sought by research institutions and industrial R&D departments focused on medicinal chemistry, agrochemical discovery, and materials science.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting kinase inhibition or other urea-based therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boronic ester reagent for constructing complex biaryl structures, a fundamental reaction in modern organic synthesis.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate urea and aryl-boronate functionalities.
• Material Science & OLED Development: Acts as a precursor for creating organic semiconductors, light-emitting materials, and other advanced functional polymers.
• Chemical Biology & Proteomics: Employed in the design of molecular probes and activity-based protein profiling (ABPP) agents to study enzyme function.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-purity boronate intermediates.

Basic Information

Product Name	1-(2,4-Dimethylphenyl)-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Urea
CAS No.	2096994-84-0
Molecular Formula	C21H27BN2O3
Molecular Weight	366.27 g/mol
Synonyms	3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(2,4-dimethylphenyl)phenylurea; 1-(2,4-Dimethylphenyl)-3-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]urea; Urea, N-(2,4-dimethylphenyl)-N'-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-; (3-((2,4-Dimethylphenyl)carbamoyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 1-(2,4-Dimethylphenyl)-3-(3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl)Urea adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP, ISO, and other relevant regulatory frameworks for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants or storing under an inert atmosphere (e.g., nitrogen or argon) to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.