Description

4-Isobutyrylphenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable boronic ester derivative. This compound serves as a crucial protected intermediate in modern organic synthesis, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the construction of complex biaryl and heterobiaryl structures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for drug discovery and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key protected boronic acid reagent for constructing active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific biaryl motifs.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and enzyme inhibitors for target identification and validation studies.
• Academic & Industrial R&D: A versatile reagent for methodological development in synthetic organic chemistry and catalysis research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a protected isobutyrylphenyl moiety.

Basic Information

Product Name	4-Isobutyrylphenylboronic Acid Pinacol Ester
CAS No.	2096341-83-0
Molecular Formula	C₁₆H₂₃BO₃
Molecular Weight	274.17 g/mol
Synonyms	4-(2-Methylpropanoyl)phenylboronic Acid Pinacol Ester; Pinacol 4-Isobutyrylphenylboronate; 4-(Isobutyryl)benzeneboronic Acid Pinacol Ester; 4-(2-Methyl-1-oxopropyl)phenylboronic Acid Pinacol Ester; 4-Isobutyrylbenzeneboronic Acid Pinacol Ester; 4-(2-Methylpropanoyl)benzeneboronic Acid Pinacol Ester; B-[4-(2-Methylpropanoyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 4-Isobutyrylphenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture ingress. Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.