Description

(6-Chloro-2-(Trifluoromethyl)Pyridin-3-Yl)Boronic Acid is a high-purity, synthetically valuable organoboronic acid derivative. This compound serves as a critical building block in modern cross-coupling reactions, enabling the efficient construction of complex molecules for advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and advanced materials chemists for the synthesis of novel active ingredients and functional materials. Its specific substitution pattern offers unique reactivity and selectivity in Suzuki-Miyaura and other palladium-catalyzed transformations.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing trifluoromethylpyridine motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Building block for creating organic electronic materials, liquid crystals, and metal-organic frameworks (MOFs) with tailored properties.
• Chemical Biology & Proteomics: Employed in the development of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Catalyst & Ligand Development: Serves as a precursor for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Custom Synthesis & Contract Manufacturing: Essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	(6-Chloro-2-(Trifluoromethyl)Pyridin-3-Yl)Boronic Acid
CAS No.	2096339-76-1
Molecular Formula	C6H4BClF3NO2
Molecular Weight	225.36 g/mol
Synonyms	3-Borono-6-chloro-2-(trifluoromethyl)pyridine; 6-Chloro-2-(trifluoromethyl)-3-pyridineboronic acid; (6-Chloro-2-(trifluoromethyl)-3-pyridinyl)boronic acid; 2-(Trifluoromethyl)-6-chloropyridine-3-boronic acid; 6-Chloro-2-trifluoromethylpyridine-3-boronic acid; Boronic acid, B-[6-chloro-2-(trifluoromethyl)-3-pyridinyl]-; 3-Pyridineboronic acid, 6-chloro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our (6-Chloro-2-(Trifluoromethyl)Pyridin-3-Yl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.