Description

2-Chloro-3-Methoxypyridine-4-Boronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. Its molecular structure, featuring both halogen and boronic acid functional groups, makes it an indispensable reagent for constructing complex heterocyclic frameworks via cross-coupling reactions. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyridine core for bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysts, and functionalized polymers.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugates for target identification and binding studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific projects requiring tailored boronic acid components.

Basic Information

Product Name	2-Chloro-3-Methoxypyridine-4-Boronic Acid
CAS No.	2096339-60-3
Molecular Formula	C6H7BClNO3
Molecular Weight	187.39 g/mol
Synonyms	(2-Chloro-3-methoxypyridin-4-yl)boronic acid; 2-Chloro-3-methoxy-4-pyridineboronic acid; 4-Borono-2-chloro-3-methoxypyridine; 2-Chloro-3-methoxypyridine-4-boronic acid pinacol ester (common derivative); 2-Chloro-3-methoxy-4-pyridinylboronic acid; 2096339-60-3; 4-Pyridineboronic acid, 2-chloro-3-methoxy-
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-3-Methoxypyridine-4-Boronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity requirements for sensitive cross-coupling applications. A Certificate of Analysis (COA) detailing purity (typically >95% by HPLC), identity confirmation, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.