Description

2-Ethoxythiazole-5-Boronic Acid Pinacol Ester is a high-value organoboron building block, specifically a protected boronic acid derivative, essential for modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel thiazole-containing molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing the thiazole heterocycle.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with thiazole motifs.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysis, and functional polymers.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical coupling partner for introducing the 2-ethoxythiazole moiety into complex molecular architectures.
• Chemical Biology & Medicinal Chemistry: Facilitates the rapid exploration of structure-activity relationships (SAR) in drug discovery programs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	2-Ethoxythiazole-5-Boronic Acid Pinacol Ester
CAS No.	2096338-64-4
Molecular Formula	C11H18BNO3S
Molecular Weight	255.14 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-ethoxythiazole; 2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; 2-Ethoxythiazol-5-ylboronic Acid Pinacol Ester; Thiazole-5-boronic Acid, 2-ethoxy-, 1,3,2-dioxaborolane, 4,4,5,5-tetramethyl- Ester; 2-Ethoxy-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)thiazole; Pinacol 2-Ethoxythiazole-5-boronate
EINECS	Contact for details

Quality Control

Our 2-Ethoxythiazole-5-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency for sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.