Description

3-Bromo-2-Fluoro-5-Trifluoromethylphenylboronic Acid is a high-value, multi-functional boronic acid derivative essential for modern synthetic chemistry. Its core value proposition lies in its role as a key building block in cross-coupling reactions, enabling the efficient construction of complex, fluorinated aromatic scaffolds. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing drug candidates, particularly those targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used to construct fluorinated aromatic cores in advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for enhanced bioactivity and metabolic stability.
• Material Science Research: Serves as a monomer or building block for developing novel fluorinated polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and bioconjugates for studying biological pathways and protein interactions.
• Catalyst Ligand Development: Acts as a starting material for creating sophisticated boronate-based ligands used in asymmetric catalysis.
• Custom Synthesis & Contract Manufacturing: A vital component for CROs and CDMOs offering bespoke chemical synthesis services to global clients.

Basic Information

Product Name	3-Bromo-2-Fluoro-5-Trifluoromethylphenylboronic Acid
CAS No.	2096338-38-2
Molecular Formula	C7H4BBrF4O2
Molecular Weight	286.82 g/mol
Synonyms	(3-Bromo-2-fluoro-5-(trifluoromethyl)phenyl)boronic acid; 2-Fluoro-3-bromo-5-(trifluoromethyl)benzeneboronic acid; 3-Bromo-2-fluoro-5-trifluoromethylbenzeneboronic acid; Boronic acid, B-[3-bromo-2-fluoro-5-(trifluoromethyl)phenyl]-; 2096338-38-2; 3-Br-2-F-5-CF3-PhB(OH)2
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-2-Fluoro-5-Trifluoromethylphenylboronic Acid is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed HPLC, NMR, and elemental analysis results are available for each lot upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.