Description

4-{[2-Chloro-6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl}Morpholine is a high-value, synthetically versatile organoboron building block designed for advanced pharmaceutical and agrochemical research. Its molecular architecture, featuring a protected boronic ester and a morpholine moiety, makes it a critical intermediate for constructing complex molecules via cross-coupling reactions. This compound is essential for medicinal chemists and process development scientists working on new active ingredients, particularly in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a building block for creating advanced organic electronic materials and functional polymers.
• Chemical Biology: Employed in the synthesis of molecular probes and tools for studying biological pathways and protein functions.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of complex organic molecules.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies.

Basic Information

Product Name	4-{[2-Chloro-6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl}Morpholine
CAS No.	2096337-89-0
Molecular Formula	C17H25BClNO3
Molecular Weight	337.65 g/mol
Synonyms	2-Chloro-6-((morpholinomethyl)phenyl)boronic acid pinacol ester; (2-Chloro-6-(morpholinomethyl)phenyl)boronic acid pinacol ester; 4-((2-Chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)morpholine; Morpholine, 4-[[2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]-; 2096337-89-0; Boronic acid, B-[2-chloro-6-[(4-morpholinyl)methyl]phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Every batch of 4-{[2-Chloro-6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl}Morpholine is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity suitable for demanding research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.