Description

(2-Amino-3-Fluoropyridin-4-Yl)Boronic Acid is a highly functionalized boronic acid derivative, serving as a crucial building block in modern synthetic chemistry. Its value lies in the strategic combination of an amino group, a fluorine atom, and a boronic acid functionality on a pyridine core, enabling precise cross-coupling reactions and the construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used to create advanced fungicides, herbicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and sensors, due to its conjugated pyridine-boronic acid structure.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and protein interactions.
• Custom Synthesis and Contract Manufacturing: A vital component for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(2-Amino-3-Fluoropyridin-4-Yl)Boronic Acid
CAS No.	2096336-62-6
Molecular Formula	C5H6BFN2O2
Molecular Weight	155.93 g/mol
Synonyms	2-Amino-3-fluoro-4-pyridineboronic acid; 4-Borono-3-fluoro-pyridin-2-amine; (2-Amino-3-fluoro-4-pyridinyl)boronic acid; 3-Fluoro-2-amino-4-pyridineboronic acid; B-(2-Amino-3-fluoropyridin-4-yl)boronic acid; 2-Amino-3-fluoropyridine-4-boronic acid; 4-Pyridineboronic acid, 2-amino-3-fluoro-
EINECS	Contact for details

Quality Control

Our (2-Amino-3-Fluoropyridin-4-Yl)Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.