Description

n-[5-Chloro-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenylmethyl]Isopropylamine is a high-purity, advanced pharmaceutical intermediate featuring a boronic ester-protected pinacol group, which is crucial for modern synthetic methodologies. This compound is specifically engineered to serve as a key building block in the synthesis of complex molecules, offering excellent stability and reactivity for cross-coupling reactions. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in Suzuki-Miyaura cross-coupling reactions to form biaryl structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific chlorinated aryl-boronate motifs.
• Material Science: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials and polymers.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing complex organic molecules, leveraging its protected boronic acid functionality.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	n-[5-Chloro-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenylmethyl]Isopropylamine
CAS No.	2096336-54-6
Molecular Formula	C16H25BClNO2
Molecular Weight	309.64 g/mol
Synonyms	1-(5-Chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)-N-isopropylpropan-1-amine; Isopropyl-[2-(5-chloro-2-pinacolatoboronbenzyl)]amine; 5-Chloro-2-((isopropylamino)methyl)phenylboronic acid pinacol ester; (5-Chloro-2-(((isopropylamino)methyl)phenyl)boronic acid pinacol ester; N-Isopropyl-1-(5-chloro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanamine
EINECS	Contact for details

Quality Control

Our production of n-[5-Chloro-2-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenylmethyl]Isopropylamine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.