Description

2-(Isopropylamino)Pyridine-4-Boronic Acid Pinacol Ester is a high-value, protected boronic acid derivative crucial for modern synthetic chemistry. This compound serves as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for the synthesis of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-couplings for constructing biaryl and heterobiaryl scaffolds found in drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring specific pyridine-based structures.
• Material Science Research: Employed in the synthesis of organic ligands for catalysts, metal-organic frameworks (MOFs), and organic electronic materials.
• Chemical Biology Probes: Serves as a building block for creating tagged molecules used in proteomics and diagnostic assay development.
• Process Chemistry & Scale-up: Utilized in route scouting and optimization for the commercial production of active pharmaceutical ingredients (APIs).
• Academic & Contract Research: A valuable reagent for methodology development and exploring new chemical spaces in academic and CRO laboratories.

Basic Information

Product Name	2-(Isopropylamino)Pyridine-4-Boronic Acid Pinacol Ester
CAS No.	2096336-19-3
Molecular Formula	C15H25BN2O2
Molecular Weight	276.19 g/mol
Synonyms	2-(Isopropylamino)-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(propan-2-ylamino)pyridine; 2-(Isopropylamino)-4-pyridineboronic acid pinacol ester; 2-(Propan-2-ylamino)pyridine-4-boronic acid pinacol ester; 2-(i-Pr-NH)-4-Py-Bpin; N-Isopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine
EINECS	Contact for details

Quality Control

Our 2-(Isopropylamino)Pyridine-4-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each lot is fully characterized by NMR (1H, 13C, 11B), HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.