Description

2-Fluoro-6-(Tetrahydropyran-4-Yloxy)Pyridine-3-Boronic Acid is a high-value, multifunctional boronic acid derivative used as a key synthetic intermediate in advanced organic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of modern pharmaceutical and agrochemical synthesis. This compound is essential for research and development chemists in the pharmaceutical industry, particularly for constructing complex heterocyclic scaffolds in drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing complex pyridine and tetrahydropyran motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where its structural features can contribute to biological activity.
• Material Science Research: Serves as a monomer or precursor for creating advanced organic electronic materials, such as those used in OLEDs or conductive polymers.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and tools for studying biological processes due to its ability to participate in selective coupling reactions.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.
• Academic & Industrial R&D: A fundamental reagent in laboratory-scale research for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	2-Fluoro-6-(Tetrahydropyran-4-Yloxy)Pyridine-3-Boronic Acid
CAS No.	2096335-76-9
Molecular Formula	C10H13BFNO3
Molecular Weight	225.03 g/mol
Synonyms	2-Fluoro-6-((tetrahydro-2H-pyran-4-yl)oxy)pyridine-3-boronic acid; 3-Pyridineboronic acid, 2-fluoro-6-[(tetrahydro-2H-pyran-4-yl)oxy]-; 2-Fluoro-6-(tetrahydropyran-4-yloxy)pyridin-3-ylboronic acid; 2-Fluoro-6-(oxan-4-yloxy)pyridine-3-boronic acid; 2096335-76-9; THP-protected fluoropyridine boronic acid; 6-(Oxan-4-yloxy)-2-fluoropyridine-3-boronic acid
EINECS	Contact for details

Quality Control

Our 2-Fluoro-6-(Tetrahydropyran-4-Yloxy)Pyridine-3-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as purity (HPLC), identity (NMR, IR), and impurity profiles. Our quality management system is designed to support cGMP and ISO standards for pharmaceutical and industrial customers.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, well-ventilated area. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm
Residue on Ignition	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.