Description

2,4-Dihydrospiro[1,5-Benzodioxepine-3,1'-Cyclopropane]-6-Boronic Acid is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic structure. This compound is a critical building block in modern organic synthesis, valued for its boronic acid functional group which enables key cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of complex organic molecules and heterocycles.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its spirocyclic framework for bioactive compound design.
• Material Science Research: Employed in the synthesis of organic electronic materials and ligands for catalytic systems.
• Chemical Biology Probes: Acts as a precursor for bioconjugation and the development of molecular probes for biochemical assays.

Basic Information

Product Name	2,4-Dihydrospiro[1,5-Benzodioxepine-3,1'-Cyclopropane]-6-Boronic Acid
CAS No.	2096335-53-2
Molecular Formula	C12H13BO4
Molecular Weight	232.04 g/mol
Synonyms	6-Borono-2,4-dihydrospiro[1,5-benzodioxepine-3,1'-cyclopropane]; Spiro[cyclopropane-1,3'-[1,5]benzodioxepin]-6'-ylboronic acid; 2,4-Dihydrospiro[1,5-benzodioxepine-3,1'-cyclopropane]-6-boronic acid; 2096335-53-2; BCP Boronic Acid; Benzodioxepine Boronic Acid Ester Precursor
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dihydrospiro[1,5-Benzodioxepine-3,1'-Cyclopropane]-6-Boronic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.