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2-(6-Butoxy-Naphthalen-2-Yl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane CAS NO 2096335-47-4


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CAS No.:2096335-47-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(6-Butoxy-Naphthalen-2-Yl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in its role as a key boronic ester derivative, enabling critical carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality precursors for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing a naphthalene core structure.
  • Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable organoboron reagent for palladium-catalyzed coupling with aryl or vinyl halides, enabling efficient construction of biaryl systems.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic frameworks.
  • Organic Light-Emitting Diodes (OLEDs): Acts as a building block for the development of advanced organic electronic materials and emissive layers.
  • Liquid Crystal and Polymer Research: Employed in the synthesis of monomers and functional materials with tailored optical and electronic properties.
  • Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry for exploring new chemical spaces and optimizing synthetic routes.

Basic Information

Product Name 2-(6-Butoxy-Naphthalen-2-Yl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No. 2096335-47-4
Molecular Formula C₂₀H₂₇BO₃
Molecular Weight 326.24 g/mol
Synonyms 2-(6-Butoxynaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Butoxy-2-naphthaleneboronic acid pinacol ester; 2-(6-n-Butoxynaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Butoxy-2-naphthylboronic acid pinacol ester; Pinacol 6-butoxynaphthalene-2-boronate; 2-(6-Butoxynaphth-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; Naphthalene-2-boronic acid, 6-butoxy-, pinacol ester
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Quality Control

Our 2-(6-Butoxy-Naphthalen-2-Yl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot quality suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥97.0% (Area %)
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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