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2-(6-Butoxy-Naphthalen-2-Yl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane CAS NO 2096335-47-4
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CAS No.:2096335-47-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-(6-Butoxy-Naphthalen-2-Yl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in its role as a key boronic ester derivative, enabling critical carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. This compound is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality precursors for constructing complex molecular architectures.
Application
- Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing a naphthalene core structure.
- Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable organoboron reagent for palladium-catalyzed coupling with aryl or vinyl halides, enabling efficient construction of biaryl systems.
- Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aromatic frameworks.
- Organic Light-Emitting Diodes (OLEDs): Acts as a building block for the development of advanced organic electronic materials and emissive layers.
- Liquid Crystal and Polymer Research: Employed in the synthesis of monomers and functional materials with tailored optical and electronic properties.
- Chemical Research & Development: A valuable tool for medicinal chemistry and process chemistry for exploring new chemical spaces and optimizing synthetic routes.
Basic Information
| Product Name | 2-(6-Butoxy-Naphthalen-2-Yl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane |
| CAS No. | 2096335-47-4 |
| Molecular Formula | C₂₀H₂₇BO₃ |
| Molecular Weight | 326.24 g/mol |
| Synonyms | 2-(6-Butoxynaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Butoxy-2-naphthaleneboronic acid pinacol ester; 2-(6-n-Butoxynaphthalen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Butoxy-2-naphthylboronic acid pinacol ester; Pinacol 6-butoxynaphthalene-2-boronate; 2-(6-Butoxynaphth-2-yl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; Naphthalene-2-boronic acid, 6-butoxy-, pinacol ester |
| EINECS | Contact for details |
Quality Control
Our 2-(6-Butoxy-Naphthalen-2-Yl)-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot quality suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥97.0% (Area %) |
| Water Content (KF) | ≤0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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