Description

1-(Tetrahydro-2H-Pyran-2-Yl)-5-Methyl-1H-Indazol-6-Yl-6-Boronic Acid is a high-purity, advanced pharmaceutical intermediate and building block for organic synthesis. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and complex molecules, particularly in medicinal chemistry and drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of targeted therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid reagent for forming carbon-carbon bonds in complex organic synthesis.
• Medicinal Chemistry Research: Used in the design and development of new chemical entities for biological screening and lead optimization.
• API Development: Integral in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical studies.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	1-(Tetrahydro-2H-Pyran-2-Yl)-5-Methyl-1H-Indazol-6-Yl-6-Boronic Acid
CAS No.	2096334-81-3
Molecular Formula	C15H19BN2O3
Molecular Weight	286.14 g/mol
Synonyms	5-Methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-ylboronic acid; 6-Borono-5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole; 1-(THP)-5-Methyl-1H-indazol-6-ylboronic acid; 1-(Tetrahydropyran-2-yl)-5-methyl-1H-indazol-6-boronic acid; 2096334-81-3; 5-Methyl-1-(oxan-2-yl)indazol-6-ylboronic acid; Boronic acid, B-[5-methyl-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-yl]-
EINECS	Contact for details

Quality Control

Our 1-(Tetrahydro-2H-Pyran-2-Yl)-5-Methyl-1H-Indazol-6-Yl-6-Boronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.