Description

2-Methyl-1-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3,6-Dihydro-2H-Pyridin-1-Yl]Propan-1-One is a high-value, advanced pharmaceutical intermediate featuring a protected boronic ester functionality. This compound is critical for enabling key carbon-carbon bond-forming reactions, such as the Suzuki-Miyaura cross-coupling, which are fundamental to modern medicinal chemistry and drug discovery. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial coupling partner for constructing biaryl and heterobiaryl structures central to many drug molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Biology Probes: Employed in the creation of tagged molecules for studying biological pathways and target engagement.
• Agrochemical Synthesis: Potential intermediate in the development of novel crop protection agents with complex heterocyclic cores.
• Material Science Research: Used in the development of organic electronic materials and advanced polymers.

Basic Information

Product Name	2-Methyl-1-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3,6-Dihydro-2H-Pyridin-1-Yl]Propan-1-One
CAS No.	2096334-79-9
Molecular Formula	C16H28BNO3
Molecular Weight	293.21 g/mol
Synonyms	1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridin-1-yl)-2-methylpropan-1-one; 2-Methyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-pyridin-1-yl)propan-1-one; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-methylpropanoyl)-1,2,3,6-tetrahydropyridine; Isobutyryl MIDA Boronate Derivative (DHP protected); Tetramethyl Dioxaborolane Pyridine Intermediate
EINECS	Contact for details

Quality Control

Our 2-Methyl-1-[4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-3,6-Dihydro-2H-Pyridin-1-Yl]Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance as a coupling partner. Certificates of Analysis (COA) with full characterization data are provided to support your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.