Description

5-Bromo-4-Cyano-2-Fluorophenylboronic Acid, Pinacol Ester is a sophisticated, multi-functional boronic ester derivative designed for advanced cross-coupling reactions. This compound matters as a critical building block in modern organic synthesis, offering a protected boronic acid group alongside bromo, cyano, and fluoro substituents for precise molecular construction. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl structures found in drug candidates.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides by introducing the phenylboronate core into target molecules.
• Materials Science Research: Serves as a monomer or building block for constructing organic electronic materials, such as OLEDs and semiconductors.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific halogen and functional group patterns.

Basic Information

Product Name	5-Bromo-4-Cyano-2-Fluorophenylboronic Acid, Pinacol Ester
CAS No.	2096334-68-6
Molecular Formula	C₁₃H₁₄BBrFNO₂
Molecular Weight	322.97 g/mol
Synonyms	5-Bromo-4-cyano-2-fluorophenylboronic acid pinacol ester; 2-Fluoro-5-bromo-4-cyanophenylboronic acid pinacol ester; (5-Bromo-4-cyano-2-fluorophenyl)boronic acid pinacol ester; 4-Bromo-5-cyano-2-fluorophenylboronic acid pinacol ester; 2096334-68-6; BRN 9081023; AKOS040759232; FT-0773297.
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Cyano-2-Fluorophenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.