Description

Butyl({[2-Chloro-6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl})Amine is a specialized organoboron building block designed for advanced synthetic chemistry. This compound matters for its role as a key intermediate in cross-coupling reactions, enabling the precise construction of complex molecular architectures. Pharmaceutical researchers and agrochemical developers need it for creating novel active ingredients, particularly in medicinal chemistry for drug discovery and development. Its unique structure combines a protected boronic ester with a chloro and amine functionality, offering versatile reactivity for targeted synthesis.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that require specific boron-containing scaffolds.
• Material Science: Serves as a monomer or precursor for advanced polymers and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the synthesis of probes and inhibitors for studying enzyme function and protein interactions.
• Ligand Synthesis: Acts as a precursor for creating novel ligands used in catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	Butyl({[2-Chloro-6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl})Amine
CAS No.	2096334-51-7
Molecular Formula	C17H27BClNO2
Molecular Weight	323.66 g/mol
Synonyms	2-Chloro-6-((butylamino)methyl)phenylboronic acid pinacol ester; N-Butyl-1-(2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanamine; Butyl[(2-chloro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl]amine; (2-Chloro-6-((butylamino)methyl)phenyl)boronic acid pinacol ester; 2096334-51-7; BRN 8280425
EINECS	Contact for details

Quality Control

Our Butyl({[2-Chloro-6-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Phenyl]Methyl})Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance for critical R&D and scale-up applications. Certificates of Analysis (COA) with full characterization data are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.