Description

2-(4-Fluoro-2-Methoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis. The CAS number for this product is 2096334-36-8.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing fluorinated aromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific fluorinated phenyl motifs.
• Material Science: Serves as a monomer or building block for creating advanced organic electronic materials, including OLEDs and organic semiconductors.
• Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura cross-coupling to form carbon-carbon bonds between aryl or vinyl groups with high efficiency and selectivity.
• Chemical Research & Development: An invaluable tool for medicinal chemists and process chemists in lead optimization and route scouting for new chemical entities.
• Ligand and Catalyst Development: Can be utilized in the synthesis of novel ligands or organometallic catalysts for asymmetric synthesis.

Basic Information

Product Name	2-(4-Fluoro-2-Methoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2096334-36-8
Molecular Formula	C₁₄H₂₀BFO₃
Molecular Weight	266.12 g/mol
Synonyms	4-Fluoro-2-methoxy-5-methylbenzeneboronic acid pinacol ester; (4-Fluoro-2-methoxy-5-methylphenyl)boronic acid pinacol ester; 5-Methyl-4-fluoro-2-methoxyphenylboronic acid pinacol ester; 2-Methoxy-4-fluoro-5-methylphenylboronic acid pinacol ester; Pinacol (4-fluoro-2-methoxy-5-methylphenyl)boronate; CAS 2096334-36-8
EINECS	Contact for details

Quality Control

Our 2-(4-Fluoro-2-Methoxy-5-Methylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistent performance for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.