Description

1-Cyclopentyl-1H-Pyrazole-5-Boronic Acid, Pinacol Ester is a high-purity, organoboron building block essential for modern synthetic chemistry. This compound matters as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronic ester.
• Pharmaceutical Intermediate: Used in the research and development of new drug candidates, particularly those containing pyrazole and cyclopentyl motifs.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with improved efficacy.
• Material Science Research: Employed in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology & Probe Development: Useful for creating labeled compounds and molecular probes for biological target identification.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries in medicinal chemistry programs.

Basic Information

Product Name	1-Cyclopentyl-1H-Pyrazole-5-Boronic Acid, Pinacol Ester
CAS No.	2096334-27-7
Molecular Formula	C14H23BN2O2
Molecular Weight	262.16 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-cyclopentyl-1H-pyrazole; 1-Cyclopentyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Cyclopentyl-1H-pyrazole-5-boronic acid pinacol ester; 1-Cyclopentyl-5-(pinacolboryl)pyrazole; Cyclopentylpyrazole boronic ester; CAS 2096334-27-7; Pyrazole boronate derivative
EINECS	Contact for details

Quality Control

Our 1-Cyclopentyl-1H-Pyrazole-5-Boronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC, to ensure high purity and consistency suitable for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry place. Allow the container to reach room temperature before opening to minimize moisture ingress. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.