Description

2-[2-(Bromomethyl)-5-Nitrophenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value, multi-functional boronic ester derivative that serves as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a reactive bromomethyl handle and a protected boronic acid moiety, makes it indispensable for constructing complex molecular architectures via cross-coupling reactions. This compound is primarily sought after by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biphenyl and heterobiaryl scaffolds found in drug candidates.
• Agrochemical Research: Used to create novel active ingredients for crop protection by introducing complex aromatic systems into target molecules.
• Material Science: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its ability to form precise carbon-carbon bonds.
• Chemical Biology & Probe Development: Utilized as a versatile building block for creating fluorescent tags, bioconjugation linkers, and molecular probes.
• Process Chemistry & Scale-up: Serves as a reliable, high-purity reagent for optimizing synthetic routes from laboratory to pilot plant scale.

Basic Information

Product Name	2-[2-(Bromomethyl)-5-Nitrophenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2096333-96-7
Molecular Formula	C₁₃H₁₇BBrNO₄
Molecular Weight	342.00 g/mol
Synonyms	(5-Nitro-2-(bromomethyl)phenyl)boronic acid pinacol ester; 2-(2-Bromomethyl-5-nitrophenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; Pinacol [2-(bromomethyl)-5-nitrophenyl]boronate; 2-(Bromomethyl)-5-nitrophenylboronic acid pinacol ester; 5-Nitro-2-(bromomethyl)benzeneboronic acid pinacol ester; 2096333-96-7; Boronic acid, B-[2-(bromomethyl)-5-nitrophenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our production of 2-[2-(Bromomethyl)-5-Nitrophenyl]-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.