Description

2-(5-Bromo-2,3-Dihydrobenzofuran-7-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 2096333-86-5 is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient, selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for biochemical and diagnostic applications.
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new synthetic pathways in organic chemistry laboratories.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, complex boronic acid derivatives.

Basic Information

Item	Detail
Product Name	2-(5-Bromo-2,3-Dihydrobenzofuran-7-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	2096333-86-5
Molecular Formula	C16H20BBrO3
Molecular Weight	351.05 g/mol
Synonyms	5-Bromo-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydrobenzofuran; 2,3-Dihydro-5-bromo-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzofuran; 5-Bromo-2,3-dihydrobenzofuran-7-boronic acid pinacol ester; 7-Boronic acid, 5-bromo-2,3-dihydrobenzofuran-, pinacol ester; (5-Bromo-2,3-dihydrobenzofuran-7-yl)boronic acid pinacol ester; B-(5-Bromo-2,3-dihydro-7-benzofuranyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(5-Bromo-2,3-Dihydrobenzofuran-7-Yl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.