Description

2-(Butylsulfanyl)Pyrimidin-5-Ylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling efficient carbon-carbon bond formation, specifically in the Suzuki-Miyaura cross-coupling reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing pyrimidine-based scaffolds found in various therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate the pyrimidine moiety.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs or conductive polymers.
• Cross-Coupling Reactions: Primarily employed in Suzuki-Miyaura cross-coupling to form biaryl and heteroaryl structures with high efficiency and selectivity.
• Chemical Biology & Proteomics: Can be utilized as a handle for bioconjugation or in the development of chemical probes and inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research laboratories for custom synthesis projects and scale-up processes.

Basic Information

Product Name	2-(Butylsulfanyl)Pyrimidin-5-Ylboronic Acid
CAS No.	2096333-75-2
Molecular Formula	C8H13BN2O2S
Molecular Weight	212.08 g/mol
Synonyms	5-(Butylthio)pyrimidine-2-boronic acid; 2-(Butylthio)-5-pyrimidineboronic acid; 2-(Butylsulfanyl)-5-pyrimidineboronic acid; (5-(Butylthio)pyrimidin-2-yl)boronic acid; B-[2-(Butylsulfanyl)pyrimidin-5-yl]boronic acid; 2096333-75-2; 2-(n-Butylsulfanyl)pyrimidin-5-ylboronic acid
EINECS	Contact for details

Quality Control

Our 2-(Butylsulfanyl)Pyrimidin-5-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Anhydrous basis)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.