Description

3-(Cyclohexylmethyl)Phenylboronic-Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound is a critical building block for constructing complex molecular architectures via cross-coupling reactions, offering enhanced stability and handling compared to its free acid form. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Serves as a versatile building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates containing substituted biphenyl motifs.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides that require specific, sterically hindered aromatic structures.
• Materials Science Research: Employed in the synthesis of organic ligands for catalysts, monomers for specialized polymers, and components for organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Useful for modifying biomolecules or creating chemical probes due to the selective reactivity of the protected boronate group.
• Process Chemistry & Scale-up: The pinacol ester protection offers improved stability and solubility, making it suitable for optimization and large-scale manufacturing processes.

Basic Information

Item	Details
Product Name	3-(Cyclohexylmethyl)Phenylboronic-Acid Pinacol Ester
CAS No.	2096333-64-9
Molecular Formula	C19H29BO2
Molecular Weight	300.25 g/mol
Synonyms	[3-(Cyclohexylmethyl)phenyl]boronic acid pinacol ester; 3-(Cyclohexylmethyl)benzeneboronic acid pinacol ester; (3-Cyclohexylmethylphenyl)boronic acid pinacol ester; Pinacol [3-(cyclohexylmethyl)phenyl]boronate; B-[3-(Cyclohexylmethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; CAS 2096333-64-9
EINECS	Contact for details

Quality Control

Every batch of 3-(Cyclohexylmethyl)Phenylboronic-Acid Pinacol Ester is manufactured and tested under a strict quality management system to ensure consistency and reliability for your critical research and production needs. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (by HPLC/NMR), identity confirmation, and impurity profiles. Our commitment to high-purity standards ensures optimal performance in sensitive cross-coupling applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). The product is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed when not in use to prevent moisture absorption and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.