Description

2-Carbamoyl-6-Fluorophenylboronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and building block for organic synthesis. This compound is valued for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing fluorinated biaryl motifs.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boron reagent for forming carbon-carbon bonds between aromatic rings in medicinal chemistry and material science research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific fluorinated aromatic components.
• Material Science: Employed in the creation of organic electronic materials, such as ligands for catalysts or monomers for specialized polymers.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and inhibitors for biochemical and pharmacological studies.

Basic Information

Product Name	2-Carbamoyl-6-Fluorophenylboronic Acid Pinacol Ester
CAS No.	2096333-57-0
Molecular Formula	C₁₃H₁₇BFNO₃
Molecular Weight	265.09 g/mol
Synonyms	2-Carbamoyl-6-fluorobenzeneboronic acid pinacol ester; (2-Carbamoyl-6-fluorophenyl)boronic acid pinacol ester; 6-Fluoro-2-(aminocarbonyl)phenylboronic acid pinacol ester; 2-Fluoro-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 2096333-57-0; B-(2-Carbamoyl-6-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Carbamoyl-6-Fluorophenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for moisture content, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.