Description

n-[3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl]Acetamide is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic ester functional group. This compound matters as a critical building block in modern medicinal chemistry, enabling the precise construction of complex molecules through cross-coupling reactions. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key boronic ester reagent for constructing biaryl and heterobiaryl structures in drug discovery.
• Pharmaceutical Intermediate: Used in the research and development of potential therapeutic agents, including kinase inhibitors and other small molecule drugs.
• Agrochemical Synthesis: Employed as a building block for creating novel active ingredients in crop protection products.
• Material Science Research: Utilized in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Acts as a precursor for synthesizing labeled compounds and probes for biological target identification.
• Process Chemistry & Scale-up: Provides a stable, handleable form of the boronic acid derivative for optimized manufacturing routes.

Basic Information

Product Name	n-[3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl]Acetamide
CAS No.	2096333-51-4
Molecular Formula	C14H21BN2O3
Molecular Weight	276.14 g/mol
Synonyms	2-Acetamido-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; N-[3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl]acetamide; 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine, N-acetyl derivative; Acetamide, N-[3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2-pyridinyl]-; 2096333-51-4; Pinacol ester of (5-Acetamido-6-methylpyridin-3-yl)boronic acid
EINECS	Contact for details

Quality Control

Our n-[3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Yl]Acetamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full analytical data are provided to support your R&D and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.