Description

3-(3-Chlorophenoxymethyl)Phenylboronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. This compound is valued for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or substituted phenyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides requiring specific chlorophenoxy architectures.
• Material Science: Serves as a precursor for creating organic electronic materials, liquid crystals, and polymers with tailored properties.
• Cross-Coupling Reactions: A specialized reagent for Suzuki-Miyaura cross-coupling, enabling the formation of carbon-carbon bonds under mild conditions.
• Chemical Research & Development: A valuable tool for medicinal chemists and process chemists in lead optimization and route scouting for complex molecules.
• Ligand Synthesis: Can be utilized in the preparation of novel ligands for catalysis and coordination chemistry.

Basic Information

Product Name	3-(3-Chlorophenoxymethyl)Phenylboronic Acid Pinacol Ester
CAS No.	2096332-64-6
Molecular Formula	C19H22BClO3
Molecular Weight	344.64 g/mol
Synonyms	3-(3-Chlorophenoxymethyl)benzeneboronic acid pinacol ester; [3-(3-Chlorophenoxymethyl)phenyl]boronic acid pinacol ester; 2-[3-(3-Chlorophenoxymethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(3-Chlorophenoxy)methylphenylboronic acid pinacol ester; Boronic acid, B-[3-[(3-chlorophenoxy)methyl]phenyl]-, 1,1-dimethylethyl ester; (3-(3-Chlorophenoxymethyl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of 3-(3-Chlorophenoxymethyl)Phenylboronic Acid Pinacol Ester is manufactured and tested under strict quality management systems to ensure batch-to-batch consistency and high purity. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.