Description

1-Butyl-1H-Pyrazole-5-Boronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, a critical building block in modern synthetic chemistry. Its primary value lies in its enhanced stability and reactivity, making it a superior reagent for demanding cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to construct complex molecular architectures for new active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl and heteroaryl compounds.
• Pharmaceutical Intermediate: Used in the research and development of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a building block for creating advanced herbicides, fungicides, and insecticides with specific activity profiles.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Useful precursor for creating novel bidentate ligands and organometallic catalysts.
• Chemical Biology Probes: Facilitates the synthesis of tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	1-Butyl-1H-Pyrazole-5-Boronic Acid, Pinacol Ester
CAS No.	2096332-26-0
Molecular Formula	C13H23BN2O2
Molecular Weight	250.15 g/mol
Synonyms	1-Butyl-5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Butyl-1H-pyrazole-5-boronic acid pinacol ester; 5-(1-Butyl-1H-pyrazol-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1-Butyl-5-(pinacolboranyl)-1H-pyrazole; 1-Butyl-1H-pyrazol-5-ylboronic acid pinacol ester; 1-Butylpyrazole-5-boronic acid pinacol ester; 1-Butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole
EINECS	Contact for details

Quality Control

Our 1-Butyl-1H-Pyrazole-5-Boronic Acid, Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C in a cool, dry, well-ventilated place. This compound is easily oxidized and should be handled with care to minimize exposure to air and moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.