Description

2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is a high-value, multifunctional boronic ester derivative that serves as a critical synthetic intermediate. Its core value proposition lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable building blocks for drug discovery, ligand synthesis, and functional polymer development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for creating biaryl and heterobiaryl structures via Suzuki-Miyaura cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific chlorinated benzoic acid motifs.
• Material Science & Organic Electronics: Serves as a precursor for organic light-emitting diodes (OLEDs), semiconductors, and conductive polymers where the boronic ester group facilitates precise molecular assembly.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes, sensors, and labeling agents due to its reactive boronate functionality.
• Ligand & Catalyst Preparation: Utilized for synthesizing specialized ligands for transition metal catalysis and other organometallic complexes.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CMOs for custom synthesis projects requiring high-purity, functionalized aromatic boronic esters.

Basic Information

Product Name	2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid
CAS No.	2096331-90-5
Molecular Formula	C13H16BClO4
Molecular Weight	282.53 g/mol
Synonyms	2-Chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid; 3-Borono-2-chlorobenzoic acid pinacol ester; 2-Chloro-3-boronobenzoic acid pinacol ester; 2-Chloro-3-(pinacolatoboryl)benzoic acid; Benzoic acid, 2-chloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 2-Chloro-3-(pinacol boronate)benzoic acid; 2-Chloro-3-boronobenzoic acid, pinacol ester; 2096331-90-5
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support research and regulatory requirements. We are committed to supplying material that meets the stringent standards expected in pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient moisture. Ideal storage temperature is between 2°C and 8°C for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.