Description

3-Isopropoxy-5-Methoxyphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its enhanced stability compared to the free boronic acid, making it an ideal reagent for Suzuki-Miyaura cross-coupling reactions under demanding conditions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, as well as in materials science for creating advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly those containing biaryl or heterobiaryl motifs via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Precursor: Enables the construction of conjugated polymers and organic semiconductors for use in OLEDs, OFETs, and photovoltaic cells.
• Ligand and Catalyst Development: Serves as a starting material for creating novel bidentate or polydentate ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological processes, leveraging the selective reactivity of the boronate ester.
• Custom Synthesis and R&D: A versatile reagent for contract research organizations (CROs) and academic laboratories exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	3-Isopropoxy-5-Methoxyphenylboronic Acid, Pinacol Ester
CAS No.	2096329-95-0
Molecular Formula	C16H25BO4
Molecular Weight	292.18 g/mol
Synonyms	(3-Isopropoxy-5-methoxyphenyl)boronic acid pinacol ester; 5-Methoxy-3-(propan-2-yloxy)phenylboronic acid pinacol ester; 3-Isopropoxy-5-methoxyphenylboronic acid neopentyl glycol ester (common alternative); Boronic acid, B-[3-(1-methylethoxy)-5-methoxyphenyl]-, 2,2-dimethyl-1,3-propanediyl ester; 3-(Isopropoxy)-5-methoxybenzeneboronic acid pinacol ester; Pinacol (3-isopropoxy-5-methoxyphenyl)boronate; CAS 2096329-95-0
EINECS	Contact for details

Quality Control

Every batch of 3-Isopropoxy-5-Methoxyphenylboronic Acid, Pinacol Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive cross-coupling applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all commercial quantities, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.