Description

N,n-Diethyl-2-Methoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is a high-purity, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex biaryl architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and organic electronic materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those requiring biaryl or heterobiaryl motifs.
• Suzuki-Miyaura Cross-Coupling Reagent: Serves as a stable organoboron partner for palladium-catalyzed carbon-carbon bond formation with aryl halides or triflates.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with complex molecular structures.
• Material Science: Intermediate in the synthesis of organic semiconductors, ligands for catalysts, and advanced polymers.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for target identification and validation.
• Process Chemistry: Scalable intermediate for the GMP production of commercial APIs under controlled conditions.

Basic Information

Product Name	N,n-Diethyl-2-Methoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide
CAS No.	2093041-46-2
Molecular Formula	C19H30BNO4
Molecular Weight	347.26 g/mol
Synonyms	2-Methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-diethylbenzamide; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methoxy-N,N-diethylbenzamide; N,N-Diethyl-2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 2093041-46-2; Benzamide, N,N-diethyl-2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Pinacol [2-methoxy-4-(diethylcarbamoyl)phenyl]boronate
EINECS	Contact for details

Quality Control

Our N,n-Diethyl-2-Methoxy-4-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications from early-stage research to cGMP production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.