Description

3-Bromo-5-Hydroxy-2-Methyl-Benzoic Acid Methyl Ester is a high-purity, synthetically valuable benzoic acid derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. It is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides, leveraging its bromo and hydroxy functional groups for structural modification.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and photoresist materials due to its aromatic core and substitutable groups.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services, supporting scale-up from gram to multi-kilogram quantities.
• Academic and Industrial R&D: Essential for medicinal chemistry programs and methodological studies in organic synthesis, such as cross-coupling reactions and ester transformations.

Basic Information

Product Name	3-Bromo-5-Hydroxy-2-Methyl-Benzoic Acid Methyl Ester
CAS No.	2092700-79-1
Molecular Formula	C10H11BrO3
Molecular Weight	259.10 g/mol
Synonyms	Methyl 3-Bromo-5-hydroxy-2-methylbenzoate; Benzoic acid, 3-bromo-5-hydroxy-2-methyl-, methyl ester; 2-Methyl-3-bromo-5-hydroxybenzoic acid methyl ester; 3-Bromo-5-hydroxy-o-toluic acid methyl ester; Methyl 3-bromo-5-hydroxy-2-methylbenzoate
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Hydroxy-2-Methyl-Benzoic Acid Methyl Ester is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Any single unknown impurity	≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.