Description

Ethanone, 1-(3-Methoxybicyclo[1.1.1]pent-1-yl)- is a specialized bicyclic ketone building block of significant interest in advanced organic synthesis. Its unique, highly strained [1.1.1]propellane-derived structure makes it a valuable precursor for constructing complex, three-dimensional molecular architectures that are difficult to access with conventional reagents. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in medicinal chemistry for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where its rigid bicyclic core can impart favorable biological activity and metabolic stability.
• Material Science Precursor: Acts as a building block for synthesizing specialty polymers and advanced organic materials with unique physical properties.
• Chemical Biology Probe Development: Employed in the creation of molecular probes and tool compounds for studying biological pathways and protein function.
• Cross-Coupling Reactions: Functions as a substrate in transition-metal catalyzed reactions, such as Suzuki or Buchwald-Hartwig couplings, to introduce the strained bicyclic moiety.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, exploring new reactions involving strained ring systems.

Basic Information

Product Name	Ethanone, 1-(3-Methoxybicyclo[1.1.1]pent-1-yl)-
CAS No.	2091508-74-4
Molecular Formula	C8H12O2
Molecular Weight	140.18 g/mol
Synonyms	1-(3-Methoxybicyclo[1.1.1]pent-1-yl)ethanone; 3-Methoxybicyclo[1.1.1]pentane-1-carbaldehyde (common misnomer); 3-Methoxy[1.1.1]propellanyl methyl ketone; Bicyclo[1.1.1]pentane, 1-acetyl-3-methoxy-; 1-Acetyl-3-methoxybicyclo[1.1.1]pentane; Methoxy[1.1.1]propellane acetophenone derivative; Research compound 2091508-74-4
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(3-Methoxybicyclo[1.1.1]pent-1-yl)- is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. Each lot is characterized by comprehensive analytical techniques including NMR, HPLC, and GC-MS. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profile is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed under an inert atmosphere to maximize shelf-life stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.