Description

2-Chloro-4-Fluoro-6-Methyl-1-Bromobenzene is a high-purity, multi-substituted benzene derivative designed for advanced organic synthesis. This compound serves as a critical building block in the development of complex molecules, offering versatile reactivity for selective functionalization. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aromatic core.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides where the specific halogen pattern influences bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, or Buchwald-Hartwig amination due to the presence of the bromo substituent.
• Chemical Library Development: Employed in high-throughput and combinatorial chemistry for generating diverse compound libraries for screening.
• Dye and Pigment Intermediate: Used in the synthesis of complex organic dyes and pigments where halogen atoms modify color and stability properties.

Basic Information

Item	Detail
Product Name	2-Chloro-4-Fluoro-6-Methyl-1-Bromobenzene
CAS No.	2090550-06-2
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	1-Bromo-2-chloro-4-fluoro-6-methylbenzene; 2-Bromo-3-chloro-5-fluorotoluene; 3-Chloro-5-fluoro-2-bromotoluene; 2-Chloro-4-fluoro-6-methylbromobenzene; Bromo(chloro)(fluoro)methylbenzene (isomer); Toluene, 2-bromo-3-chloro-5-fluoro-; Contact for additional synonyms
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-6-Methyl-1-Bromobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Area %)
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.